Low VWF: an established mild bleeding disorder?

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چکیده

منابع مشابه

Diagnosis of mild bleeding disorders.

The precise diagnosis of a severe haemorrhagic disorder is usually not too problematic. However, physicians are most often faced with individuals consulting for mild haemorrhagic symptoms, particularly occurring after a surgical intervention. The problem here is to evaluate whether this person really has a bleeding disorder requiring special investigations and treatments, particularly if anothe...

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How to estimate bleeding risk in mild bleeding disorders.

The concept of mild bleeding disorders (MBD) has evolved in contrast to severe hemophilia A and B to indicate less severe disorders, characterized by the presence of more frequent and/or more prominent bleeding symptoms than in the normal population. These symptoms occur mostly after a recognizable challenge and do not lead to major discomfort or organ damage, even in the absence of specific me...

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Diagnosis and management of mild bleeding disorders.

Mild bleeding disorders are a common reason for a referral to a hematologist and these conditions can be challenging to evaluate. Recent research has highlighted that some bleeding symptoms are quite common in the general population and that there is clinical variability in symptom expression among individuals with defined bleeding problems. Moreover, bleeding risks for many bleeding disorders ...

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Acquired hemophilia A: an underdiagnosed, severe bleeding disorder.

Acquired hemophilia is a rare bleeding disorder caused by autoantibodies that inhibit coagulation factor VIII. In most cases, it manifests with severe, often life‑threatening bleeds. Acquired hemophilia may be idiopathic or secondary to another condition, most commonly other autoimmune disease or cancer. Treatment is directed to stop bleeding and eradicate inhibitory autoantibodies. Like in mos...

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Risk factors of mild rectal bleeding in very low birth weight infants: a case control study

BACKGROUND Mild rectal bleeding (MRB) is a particular clinical entity different from necrotizing enterocolitis, which significantly influences neonatal care in preterm infants. We aimed to determine the risk factors and to evaluate prospectively the clinical course of MRB. METHODS We consecutively included in a case-control study all infants with birth weight ≤ 1500 g or gestational age ≤ 32 ...

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ژورنال

عنوان ژورنال: Blood

سال: 2017

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2017-09-807180